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Human sympathetic ganglion organoids support investigation of sympathetic innervation of target organs
08 January 2026 While the human central nervous system (CNS) has often been modelled with organoids, progress in constructing the peripheral nervous system (PNS) has been relatively limited. Yet, the PNS plays a crucial role in communication between different areas of the body and the brain and dysfunction in PNS has been tied to a number of chronic diseases. The PNS has two main subsystems, one of which is the autonomic nervous system, which automatically controls physio
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