3D tissue platforms

Covers latest advances in human 3D tissue platforms

A person sketched in black and white colour holds their head, looking troubled. His thoughts are visually represented by blue lines that intersect chaotically, suggesting the person suffers from cognitive impairment related to Alzheimer's disease. Beneath his eyes, 6 abstract pattern lines of different blue shades progress toward him. These lines symbolize the 6 distinct hiPSC-derived cell lines that researchers have used to engineer a 3D immuno-glial-neurovascular human brain model for preclinical research into neurodegenerative disorders.

3D immuno-glial-neurovascular human brain platform for high-fidelity disease modelling

17 October 2025 Neurodegenerative disorders, such as Alzheimer’s disease (AD), are highly debilitating, progressive disorders that affect cognitive function and behaviour. Traditionally, biomedical research into AD has relied on animals to model AD pathophysiology and develop treatments. However, none of the treatments tested in AD animal models were able to halt or reverse cognitive decline in AD patients. The failure rate in clinical trials of drugs developed and validat

3D tissue platforms