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Adaptive and context-aware volumetric printing enhances functional relevance of 3D bioprinted human tissues
03 September 2025 The technique of 3D bioprinting of living tissues to recapitulate the structure and function of human organs has shown great promise in disease modelling, drug testing and regenerative medicine. To further enhance the viability, complexity and functional relevance of bioprinted constructs, Riccardo Levato’s team at UMC Utrecht and Utrecht University have developed an innovative modelling methods termed Generative, Adaptive, Context-Aware 3D printing (GRAC


3D immuno-glial-neurovascular human brain platform for high-fidelity disease modelling
17 October 2025 Neurodegenerative disorders, such as Alzheimer’s disease (AD), are highly debilitating, progressive disorders that affect cognitive function and behaviour. Traditionally, biomedical research into AD has relied on animals to model AD pathophysiology and develop treatments. However, none of the treatments tested in AD animal models were able to halt or reverse cognitive decline in AD patients. The failure rate in clinical trials of drugs developed and validat


Genetic Engineering Unlocks Organotypic Vascularization
02 October 2025 Microvessels - capillaries and post‑capillary venules - are the smallest vessels in the circulation, with a cellular composition and thin-walled structure that enables nutrient exchange, oxygen delivery, waste removal, and immune‑cell trafficking between the blood and surrounding tissue cells. The absence of microvascular function is often cited as a major bottleneck of in vitro preclinical models, leading to tissue necrosis and limiting physiological releva
UMC Utrecht receives €2.3M grant to advance its generative, context-aware 3D bioprinting method
09 December 2025 Riccardo Levato’s team at UMC Utrecht and Utrecht University receives an ERC Consolidator Grant of approx. €2.3M to advance the next phase of its innovative method of generative, context-aware 3D bioprinting. The technique of 3D bioprinting of living tissues to recapitulate the structure and function of human organs has shown great promise in disease modelling, drug testing and regenerative medicine. Supported by a 2020 ERC Starting Grant, Riccardo Lev
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