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Autologous human tumor-immune organoid model for patient-specific prediction of response to immunotherapy
27 January 2026 Despite important investment in biomedical research, the most common malignant adult brain tumor - glioblastoma (GBM) - remains largely refractory to existing treatments. Tumors can evade or suppress immunity through a variety of mechanisms, including antigen heterogeneity and immunosuppressive signaling. Owing in large part to inter-species differences in the immune system and the tumor microenvironment (extracellular matrix composition, stromal cells beha


3D immuno-glial-neurovascular human brain platform for high-fidelity disease modelling
17 October 2025 Neurodegenerative disorders, such as Alzheimer’s disease (AD), are highly debilitating, progressive disorders that affect cognitive function and behaviour. Traditionally, biomedical research into AD has relied on animals to model AD pathophysiology and develop treatments. However, none of the treatments tested in AD animal models were able to halt or reverse cognitive decline in AD patients. The failure rate in clinical trials of drugs developed and validat
Genoskin raises $8.7M to advance immunocompetent human skin models
16 September 2025 Franco-American CRO Genoskin announces it has raised $8.7M in its first funding round led by OCCTE (FPCI Occidev Impacts) to grow its human ex vivo skin platform. In a field that struggles to bridge the gap between preclinical promise and clinical outcome, the project carried by Genoskin has a particular significance. The development of vaccines and therapies for human skin diseases is fraught with difficulties, not least of which is the existence of n
Parallel Bio raises $21M to expand its human immune organoid platform
12 June 2025 Cambridge, Massachusetts-based Parallel Bio announces it has raised $21 million Series A funding to scale up and automate the production of its immune organoid in vitro platform. This funding round led by AIX Ventures was supported by prominent leaders in AI and biotech, including Marc Benioff, founder and CEO of Salesforce. Beyond infections and autoimmune diseases, it is widely recognized that the human immune systems plays a key role in a great number of
Qureator's preclinical tumor model featured in world's first animal-free IND approval
27 October 2025 As we enter a new era of drug discovery, where IND authorization can now be granted based on human data only, marking a clean departure from mandatory animal testing, Qureator's human organ-on-chip platform has laid the groundwork for the world’s first IND approval of its kind . The IND grant concerns SillaJen's BAL0891-tislelizumab combination therapy to treat solid tumors. Qureator's patient-derived vascularized tumor immune microenvironment (TME) model
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