17 October 2025   Neurodegenerative disorders, such as Alzheimer’s disease  (AD), are highly debilitating, progressive disorders that affect cognitive function and behaviour. Traditionally, biomedical research into AD has relied on animals to model AD pathophysiology and develop treatments. However, none of the treatments tested in AD animal models were able to halt or reverse cognitive decline in AD patients. The failure rate in clinical trials of drugs developed and validat

02 October 2025   Microvessels - capillaries and post‑capillary venules - are the smallest vessels in the circulation, with a cellular composition and thin-walled structure that enables nutrient exchange, oxygen delivery, waste removal, and immune‑cell trafficking between the blood and surrounding tissue cells. The absence of microvascular function is often cited as a major bottleneck of in vitro preclinical models, leading to tissue necrosis and limiting physiological releva

18 November 2025   Emulate, Inc.  the pioneer of organ-on-a-chip technology, announces the launch of its Brain-Chip R1 platform, marketed as a first-in-class comprehensive model of the neurovascular unit. This latest organ-on-chip model provides the means for human-relevant drug discovery, assessment of drug transport across the blood-brain barrier (BBB), and investigation of mechanisms of neuroinflammation.   This is particularly important since human neurological diseases,